Article
Article
Adeno-SV40 hybrid virus
Article By:
Melnick, Joseph L. Department of Virology and Epidemiology, Baylor College of Medicine, Houston, Texas.
Last reviewed:August 2019
DOI:https://doi.org/10.1036/1097-8542.010750
A type of defective virus particle in which part of the genetic material of papovavirus SV40 is encased within an adenovirus protein coat (capsid). Human adenoviruses require human cells for their propagation; however, papovavirus SV40 can serve as a “helper,” enabling human adenoviruses to replicate in monkey cells.
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