Article
Article
Atomic force microscopy
Article By:
Dufrêne, Yves F. Université catholique de Louvain, Louvain-la-Neuve, Belgium.
Last reviewed:October 2019
DOI:https://doi.org/10.1036/1097-8542.801300
A form of microscopy in which a sharp tip is scanned over the surface of a sample while sensing the interaction force between the tip and the sample. Due to its ability to observe and manipulate surfaces in aqueous solution, atomic force microscopy (AFM) has revolutionized the way in which microscopists explore biological structures, from single molecules to living cells.
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