Article
Article
Immunological ontogeny
Article By:
Gelfand, Erwin W. Division of Immunology and Rheumatology, Hospital for Sick Children, Toronto, Ontario, Canada.
Last reviewed:January 2020
DOI:https://doi.org/10.1036/1097-8542.338665
The origin and development (ontogeny) of the lymphocyte system, from its earliest stages to the two major populations of mature lymphocytes: the thymus-dependent or T lymphocytes, and the thymus-independent or B lymphocytes. The T lymphocytes carry out those aspects of function which are called cell-mediated immunity, including graft rejection, elimination of tumor cells, and delayed hypersensitivity. B cells are responsible for humoral or antibody-mediated immunity. See also: Immunity
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