Article
Article
Perilipin
Article By:
Kimmel, Alan R. Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Sztalryd, Carole Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland.
Last reviewed:February 2022
DOI:https://doi.org/10.1036/1097-8542.497950
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- Perilipins as primary regulators of cellular lipid storage, published June 2014:Download PDF
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A regulator of cellular lipid storage and the major surface coat protein of cytoplasmic lipid droplets. Perilipins (derived from the Greek words for “surrounding lipid”) are primary regulators of cellular lipid storage. The perilipins sequester lipids by protecting cytoplasmic lipid droplets (CLDs) from lipase action. Their relative protective nature and expression are adapted to the balance of lipid storage and utilization in specific cells.
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