Article
Article
- Biology & Biomedicine
- Biochemistry and molecular biology
- Retinoid receptor
Retinoid receptor
Article By:
Halldorsdottir, Solveig Division of Molecular Genetics, Department of Pediatrics, Columbia University, New York, New York.
Blaner, William S. Department of Medicine, Columbia University, Presbyterian Hospital, New York, New York.
Last reviewed:August 2020
DOI:https://doi.org/10.1036/1097-8542.800920
- Receptor structure and distribution
- Mechanism of transcriptional regulation
- Physiologic actions
- Clinical applications
- Related Primary Literature
- Additional Reading
A protein in the cell nucleus that mediates the actions of retinoids (the natural and synthetic analogs of vitamin A) by regulating the rates of transcription of retinoid-responsive genes. Retinoid receptors facilitate the normal biological actions of vitamin A within the body. Thus, they play an important role in the maintenance of normal growth and development; in the immune response; in male and female reproduction; in blood cell development; in the maintenance of healthy skin and bones; and ultimately in the general good health of the organism. See also: Vitamin
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