Article
Article
Sendai virus
Article By:
Ishida, Nakao Department of Bacteriology, Tohoku University School of Medicine, Sendai, Japan.
Last reviewed:June 2020
DOI:https://doi.org/10.1036/1097-8542.614350
A member of the viruses in the type species Parainfluenza 1, genus Paramyxovirus, family Paramyxoviridae; it is also called hemagglutinating virus of Japan (HVJ). Sendai virus was originally recovered in Sendai, Japan, from mice inoculated with autopsy specimens from newborns who died of fatal pneumonitis in an epidemic in 1952. Subsequent attempts to isolate this virus from humans were, however, mostly unsuccessful, although mice are commonly infected with Sendai virus along with rats, guinea pigs, hamsters, and pigs. It is believed that the natural host of Sendai virus is the mouse and that the virus is usually nonpathogenic for humans.
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