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- Engineering & Materials
- Environmental engineering
- Data-mining and informatics approaches for environmental contaminants
- Health Sciences
- Hygiene and public health
- Data-mining and informatics approaches for environmental contaminants
Data-mining and informatics approaches for environmental contaminants
Article By:
Chang, Daniel T. National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina.
Goldsmith, Michael-Rock National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina.
Fraile Rodriguez, Arantxa Department of Fundamental Physics and Institute of Nanoscience and Technology, University of Barcelona, Catalonia, Spain.
Grulke, Christopher M. National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina.
Egeghy, Peter P. National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina.
Mitchell-Blackwood, Jade College of Engineering, Michigan State University, East Lansing, Michigan.
Last reviewed:October 2021
DOI:https://doi.org/10.1036/1097-8542.180930
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- Data-mining and informatics approaches for environmental contaminants, published June 2014:Download PDF
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- Data mining and informatics
- Chemical space and cheminformatics
- Exposure science and pharmacokinetics
- The nature of chemicals
- Related Primary Literature
- Additional Reading
The use of data analytics and informatics-based approaches to discriminate between potential environmental contaminants and noncontaminants. New and emerging environmental contaminants are chemicals that have not been previously detected or that are being detected at levels significantly different from those expected in both biological and ecological arenas (that is, human, wildlife, and environment). Many chemicals can originate from a variety of sources, including consumer, agriculture, and industry as well as natural and/or anthropogenic disaster scenarios. For example, endocrine-disrupting chemicals (EDCs), pharmaceuticals, and personal care products (such as therapeutic, nontherapeutic, and veterinary drugs, as well as cosmetics and fragrances) are known to be present in many of the world's water bodies and thought to originate from a variety of sources, including improper disposal into municipal sewage, agribusiness, and veterinary practices. The detection and quantification of these chemicals from a toxicology and exposure perspective is paramount to understanding their effects on both the ecosystem and human health. EDCs act on the endocrine system and are known to alter sexual development and fertility in many vertebrate species. It is suspected that they may play a role in species population decline as well as public health issues. See also: Environmental toxicology; Toxicology
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