Rowen, Lee Institute for Systems Biology, Seattle, Washington.
Hood, Leroy Institute for Systems Biology, Seattle, Washington.
Last reviewed:September 2021
- Scientific approach
- Genomics and systems biology
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The comprehensive analysis of an organism's genome (full genetic content). Genomics is the scientific field of molecular biology dealing with an organism's complete set of genetic content, or genome, which includes (but is not limited to) its genes and the signaling codes regulating gene expression. In general, an organism's genome includes the full complement of inherited information-bearing genetic material residing in that organism's chromosomes. Thus, genomics encompasses all aspects related to the genome, including genomic structure, function, and mapping (Fig. 1). In addition, genomics (as a discipline) focuses on an organism's entire set of genes rather than on individual genes. The term genomics was coined in 1986 to name a journal oriented to the mapping, sequencing, and analysis of genomes. See also: Chromosome; Gene; Genetic code; Genetic mapping; Genetics; Molecular biology
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